Clinical Information Support System (CISS) is a web-based portal application that provides a framework of services for the VA enterprise and supplies an integration point for its partner systems. The initial CISS partner system is the Occupational Health Record-keeping System (OHRS), a web-based application that enables employee occupational health staff to create, maintain, and monitor medical records for VA employees and generate national, Veterans Integrated Service Network (VISN), and site-specific reports.The CISS portal is development in the delivery of information and applications to the clinical user community. It provides a single point of access for the clinical user's application and information needs, facilitating faster and more efficient patient care.The CISS framework further establishes a foundation for publishing any type of application, including clinical, non-clinical, HealtheVet, and legacy applications. These plug-in applications, called 'partner systems', can be developed independently and published to the users through the CISS portal. The CISS Program development team uses repeatable Agile development, management and support processes to rapidly develop quality software in 6-month release cycles, improving efficiency and customer satisfaction.